ISCA2

Across TCGA patient cohorts, ISCA2 protein abundance is significantly associated with the protein abundance of many other proteins, with 15,799 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ISCA2-associated proteins across cancer lineages are DLST, GLRX5, and TIMM9. Each is linked with ISCA2 in more than 9 cancer types. Because this analysis shows association rather than direction, both ISCA2-to-partner and partner-to-ISCA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ISCA2 versus DLST in CCRCC, with a Pearson correlation of 0.68.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ISCA2→partner) and Y-score (partner→ISCA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	DLST →	+0.329	+0.344	<.001	<.001	3	10
LSCC	GLRX5 →	+0.472	+0.353	<.001	<.001	3	9
BRCA	TIMM9 →	+0.417	+0.490	<.001	<.001	3	9
LSCC	UQCRFS1 →	+0.361	+0.342	<.001	<.001	3	9
OV	IBA57 →	+0.472	+0.485	.001	.001	2	9
LUAD	GSTZ1 →	+0.531	+0.436	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,799 associations by consensus.

ISCA2 vs DLST — CCRCC

Explore this scatter interactively →