IRX6

Across TCGA patient cohorts, IRX6 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,061 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IRX6-associated proteins across cancer lineages are FAP, TLN2, and TRIM2. Each is linked with IRX6 in more than 3 cancer types. Because this analysis shows association rather than direction, both IRX6-to-partner and partner-to-IRX6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRX6 versus FAP in OV, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IRX6→partner) and Y-score (partner→IRX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FAP →	+0.746	+0.517	<.001	<.001	3	4
HNSC	TLN2 →	+0.446	+0.820	<.001	<.001	3	3
LSCC	TRIM2 →	+0.670	+1.235	<.001	<.001	3	3
LSCC	TRIM2_T371 →	+1.003	+1.262	<.001	.001	3	3
BRCA	ZNF652_S204 →	-0.630	-0.787	.006	.005	3	3
COAD	SPAG1 →	-0.446	-0.046	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,061 associations by consensus.

IRX6 vs FAP — OV

Explore this scatter interactively →