IRX2

Across TCGA patient cohorts, IRX2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,505 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IRX2-associated genes across cancer lineages are RAB3IP, C5orf38, and IRX1. Each is linked with IRX2 in more than 2 cancer types. Because this analysis shows association rather than direction, both IRX2-to-partner and partner-to-IRX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRX2 versus RAB3IP in LUAD, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IRX2→partner) and Y-score (partner→IRX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RAB3IP →	+0.686	+0.554	<.001	.001	3	3
BRCA	C5orf38 →	+1.444	+0.967	<.001	<.001	3	3
LUAD	IRX1 →	+1.207	+0.699	<.001	<.001	3	2
LSCC	MIR30B →	+1.134	+0.758	<.001	.001	3	2
LUAD	IGFALS →	+0.775	+0.499	<.001	<.001	3	2
BRCA	NNT →	+0.523	+0.572	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,505 associations by consensus.

IRX2 vs RAB3IP — LUAD

Explore this scatter interactively →