IRX1

Across TCGA patient cohorts, IRX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,106 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IRX1-associated proteins across cancer lineages are IRX1_S447, C11orf96, and CADM1. Each is linked with IRX1 in more than 5 cancer types. Because this analysis shows association rather than direction, both IRX1-to-partner and partner-to-IRX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRX1 versus IRX1_S447 in LSCC, with a Pearson correlation of 0.79.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IRX1→partner) and Y-score (partner→IRX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	IRX1_S447 →	+1.783	+2.350	<.001	<.001	3	6
CCRCC	C11orf96 →	+0.612	+0.340	<.001	.002	3	5
COAD	CADM1 →	+0.736	+0.016	<.001	.005	3	5
GBM	IRX1_S267 →	+1.909	+3.255	<.001	<.001	3	5
LUAD	TMOD1 →	+0.511	+0.921	<.001	<.001	3	4
PDAC	ABI3BP →	+0.655	+0.160	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,106 associations by consensus.

IRX1 vs IRX1_S447 — LSCC

Explore this scatter interactively →