Across TCGA patient cohorts, IRS3P RNA expression is significantly associated with the go_rna of many other GO terms, with 7,136 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IRS3P-associated GO terms across cancer lineages are Oxidative phosphorylation, Proton motive force-driven ATP synthesis, and Spermidine metabolic process. Each is linked with IRS3P in more than 22 cancer types. Because this analysis shows association rather than direction, both IRS3P-to-partner and partner-to-IRS3P results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IRS3P→partner) and Y-score (partner→IRS3P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Oxidative phosphorylation →	+0.070	+0.314	<.001	<.001	3	23
STAD	Proton motive force-driven ATP synthesis →	+0.074	+0.342	<.001	<.001	3	21
STAD	Spermidine metabolic process →	+0.051	+0.357	<.001	<.001	3	20
STAD	Mitochondrial respiratory chain complex assembly →	+0.062	+0.354	<.001	<.001	3	20
STAD	Protein localization to basolateral plasma membrane →	+0.057	+0.314	<.001	<.001	3	20
STAD	Nucleoside triphosphate biosynthetic process →	+0.065	+0.316	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,136 associations by consensus.

Exploration

IRS3P survival (RNA) · tumor vs normal (RNA) · all IRS3P data types