IRS2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IRS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,350 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IRS2-associated proteins across cancer lineages are IRS2_S1100, IRS2_S560, and IRS2_S577. Each is linked with IRS2 in more than 9 cancer types. Because this analysis shows association rather than direction, both IRS2-to-partner and partner-to-IRS2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IRS2→partner) and Y-score (partner→IRS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADIRS2_S1100 →+1.429+1.209<.001<.001310
OVIRS2_S560 →+0.891+1.304<.001<.001310
OVIRS2_S577 →+1.044+1.476<.001<.001310
CCRCCIRS2_S365 →+1.246+0.999<.001<.00139
UCECIRS2_S608 →+1.926+3.156.005.00939
UCECIRS2_S679 →+0.852+1.417<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,350 associations by consensus.

Exploration