IRF7

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IRF7 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,895 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IRF7-associated proteins across cancer lineages are OAS3, CMPK2, and DDX58. Each is linked with IRF7 in more than 9 cancer types. Because this analysis shows association rather than direction, both IRF7-to-partner and partner-to-IRF7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IRF7→partner) and Y-score (partner→IRF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMOAS3 →+0.657+0.563<.001<.001310
HNSCCMPK2 →+0.667+1.208<.001<.00139
HNSCDDX58 →+0.702+1.025<.001<.00139
GBMDTX3L →+0.483+0.743<.001<.00139
HNSCIFIT1 →+0.897+1.141<.001<.00139
HNSCIFIT2 →+0.922+1.133<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,895 associations by consensus.

Exploration