IRF2BPL

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IRF2BPL protein abundance is significantly associated with the RNA expression of many other genes, with 15,283 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible IRF2BPL-associated genes across cancer lineages are SNW1, TTLL5, and MED6. Each is linked with IRF2BPL in more than 7 cancer types. Because this analysis shows association rather than direction, both IRF2BPL-to-partner and partner-to-IRF2BPL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRF2BPL versus SNW1 in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IRF2BPL→partner) and Y-score (partner→IRF2BPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVSNW1 →+0.590+0.377<.001<.00138
LUADTTLL5 →+0.458+0.329<.001.00137
LUADMED6 →+0.437+0.414<.001<.00137
OVSNHG10 →+0.481+0.381.002.00137
HNSCALKBH1 →+0.479+0.229.005.00137
BRCAZC3H14 →+0.433+0.344<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,283 associations by consensus.

IRF2BPL vs SNW1 — OV

Per-sample scatter of IRF2BPL vs SNW1 in OV (Pearson r = 0.40).

Explore this scatter interactively →

Exploration