IRF2BP2

Across TCGA patient cohorts, IRF2BP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,229 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IRF2BP2-associated proteins across cancer lineages are RBBP5, RCOR3, and IRF2BP2_S360. Each is linked with IRF2BP2 in more than 6 cancer types. Because this analysis shows association rather than direction, both IRF2BP2-to-partner and partner-to-IRF2BP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRF2BP2 versus RBBP5 in HNSC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IRF2BP2→partner) and Y-score (partner→IRF2BP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RBBP5 →	+0.291	+1.002	<.001	<.001	3	7
HNSC	RCOR3 →	+0.410	+0.767	<.001	<.001	3	7
HNSC	IRF2BP2_S360 →	+0.507	+0.911	<.001	<.001	3	7
LSCC	DHX9 →	+0.305	+0.564	<.001	<.001	3	7
GBM	NONO →	+0.177	+0.320	.002	.006	2	7
GBM	POGZ →	+0.234	+0.396	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,229 associations by consensus.

IRF2BP2 vs RBBP5 — HNSC

Explore this scatter interactively →