IRF2BP2

Across TCGA patient cohorts, IRF2BP2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,057 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible IRF2BP2-associated genes across cancer lineages are UTP25, DESI2, and URB2. Each is linked with IRF2BP2 in more than 7 cancer types. Because this analysis shows association rather than direction, both IRF2BP2-to-partner and partner-to-IRF2BP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRF2BP2 versus UTP25 in LSCC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IRF2BP2→partner) and Y-score (partner→IRF2BP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UTP25 →	+0.593	+0.277	<.001	<.001	3	8
LSCC	DESI2 →	+0.564	+0.273	<.001	<.001	3	7
LSCC	URB2 →	+0.642	+0.228	<.001	.002	3	7
BRCA	TP53BP2 →	+0.697	+0.220	.003	.001	3	7
HNSC	NUP133 →	+0.988	+0.323	.001	<.001	3	7
LUAD	UBAP2L →	+0.525	+0.237	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,057 associations by consensus.

IRF2BP2 vs UTP25 — LSCC

Explore this scatter interactively →