IRF2BP2

Across TCGA cell cohorts, IRF2BP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,977 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IRF2BP2-associated GO terms across cancer lineages are Negative regulation of cardiac muscle hypertrophy, Glucose homeostasis, and Response to epidermal growth factor. Each is linked with IRF2BP2 in more than 9 cancer types. Because this analysis shows association rather than direction, both IRF2BP2-to-partner and partner-to-IRF2BP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cardiac muscle hypertrophy grouped by IRF2BP2-low versus IRF2BP2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IRF2BP2→partner) and Y-score (partner→IRF2BP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cardiac muscle hypertrophy →	+0.090	+0.766	.002	<.001	3	10
STOMACH	Glucose homeostasis →	+0.046	+1.054	<.001	.001	3	10
LARGE_INTESTINE	Response to epidermal growth factor →	+0.084	+0.829	<.001	<.001	3	9
LARGE_INTESTINE	Negative regulation of stem cell differentiation →	+0.132	+0.917	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Negative regulation of erythrocyte differentiation →	+0.122	+0.509	.001	.008	3	9
UPPER_AERODIGESTIVE_TRACT	Protein destabilization →	+0.077	+0.653	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,977 associations by consensus.

Negative regulation of cardiac muscle hypertrophy by IRF2BP2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →