IRF2BP1

Across TCGA patient cohorts, IRF2BP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,178 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IRF2BP1-associated proteins across cancer lineages are PPP5C, IRF2BP1_S384, and XRCC1. Each is linked with IRF2BP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both IRF2BP1-to-partner and partner-to-IRF2BP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRF2BP1 versus PPP5C in OV, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IRF2BP1→partner) and Y-score (partner→IRF2BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PPP5C →	+0.384	+0.815	<.001	.003	3	7
BRCA	IRF2BP1_S384 →	+0.546	+0.665	<.001	<.001	3	7
GBM	XRCC1 →	+0.417	+0.531	<.001	<.001	3	6
GBM	PARP4 →	-0.445	-0.502	<.001	<.001	3	6
OV	PNKP →	+0.440	+0.759	<.001	.004	3	5
LSCC	POGZ →	+0.311	+0.732	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,178 associations by consensus.

IRF2BP1 vs PPP5C — OV

Explore this scatter interactively →