IRF2BP1

Across TCGA patient cohorts, IRF2BP1 protein abundance is significantly associated with the RNA expression of many other genes, with 19,685 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IRF2BP1-associated genes across cancer lineages are PPP5C, ZNF180, and CD74. Each is linked with IRF2BP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both IRF2BP1-to-partner and partner-to-IRF2BP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRF2BP1 versus PPP5C in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IRF2BP1→partner) and Y-score (partner→IRF2BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PPP5C →	+0.596	+0.283	<.001	<.001	3	7
OV	ZNF180 →	+0.885	+0.402	<.001	<.001	3	7
LSCC	CD74 →	-1.057	-0.366	<.001	<.001	3	7
LSCC	PGBD1 →	+0.772	+0.307	<.001	<.001	3	7
HNSC	ZSCAN26 →	+0.689	+0.289	<.001	<.001	3	7
OV	CCNB1IP1 →	+0.797	+0.294	.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,685 associations by consensus.

IRF2BP1 vs PPP5C — OV

Explore this scatter interactively →