IRF2BP1

Across TCGA cell cohorts, IRF2BP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,764 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IRF2BP1-associated GO terms across cancer lineages are Transcription initiation-coupled chromatin remodeling, Regulation of glucose mediated signaling pathway, and Positive regulation of glucose mediated signaling pathway. Each is linked with IRF2BP1 in more than 15 cancer types. Because this analysis shows association rather than direction, both IRF2BP1-to-partner and partner-to-IRF2BP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription initiation-coupled chromatin remodeling grouped by IRF2BP1-low versus IRF2BP1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IRF2BP1→partner) and Y-score (partner→IRF2BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Transcription initiation-coupled chromatin remodeling →	+0.085	+0.846	<.001	.001	3	16
BONE	Regulation of glucose mediated signaling pathway →	+0.155	+1.347	<.001	<.001	3	16
BONE	Positive regulation of glucose mediated signaling pathway →	+0.155	+1.347	<.001	<.001	3	16
CNS	Negative regulation of calcium ion export across plasma membrane →	+0.087	+1.065	<.001	<.001	3	16
STOMACH	Positive regulation of T-helper 17 cell lineage commitment →	+0.243	+1.193	.002	.001	3	15
BONE	Regulation of protein localization to centrosome →	+0.098	+0.964	.003	.008	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,764 associations by consensus.

Transcription initiation-coupled chromatin remodeling by IRF2BP1 expression — OVARY

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