IRAK3

Across TCGA patient cohorts, IRAK3 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,412 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IRAK3-associated proteins across cancer lineages are TBXAS1, TBC1D2B, and PNN. Each is linked with IRAK3 in more than 6 cancer types. Because this analysis shows association rather than direction, both IRAK3-to-partner and partner-to-IRAK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRAK3 versus TBXAS1 in GBM, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IRAK3→partner) and Y-score (partner→IRAK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TBXAS1 →	+0.568	+1.041	<.001	<.001	3	7
UCEC	TBC1D2B →	+0.394	+1.018	<.001	<.001	3	7
GBM	PNN →	-0.359	-1.003	<.001	<.001	3	7
PDAC	RCSD1_S179 →	+0.667	+0.438	.001	.002	3	7
PDAC	RPS4X →	-0.354	-0.369	.001	.005	3	7
OV	WIPF1 →	+0.554	+1.102	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,412 associations by consensus.

IRAK3 vs TBXAS1 — GBM

Explore this scatter interactively →