IRAK3

Across TCGA patient cohorts, IRAK3 protein abundance is significantly associated with the RNA expression of many other genes, with 18,938 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IRAK3-associated genes across cancer lineages are RBMS1P1, SAA2, and MEFV. Each is linked with IRAK3 in more than 6 cancer types. Because this analysis shows association rather than direction, both IRAK3-to-partner and partner-to-IRAK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRAK3 versus RBMS1P1 in UCEC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IRAK3→partner) and Y-score (partner→IRAK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RBMS1P1 →	+1.339	+0.514	<.001	<.001	3	7
GBM	SAA2 →	+2.088	+0.442	<.001	<.001	3	6
PDAC	MEFV →	+0.725	+0.331	<.001	<.001	3	5
BRCA	KYNU →	+1.115	+0.423	.003	.006	3	5
GBM	CCRL2 →	+0.729	+0.459	.009	<.001	3	5
LSCC	FCGR3B →	+1.360	+0.265	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,938 associations by consensus.

IRAK3 vs RBMS1P1 — UCEC

Explore this scatter interactively →