IRAK3

Across TCGA cell cohorts, IRAK3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,502 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IRAK3-associated GO terms across cancer lineages are Regulation of intracellular transport, Regulation of syncytium formation by plasma membrane fusion, and Mitochondrial electron transport, cytochrome c to oxygen. Each is linked with IRAK3 in more than 9 cancer types. Because this analysis shows association rather than direction, both IRAK3-to-partner and partner-to-IRAK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intracellular transport grouped by IRAK3-low versus IRAK3-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IRAK3→partner) and Y-score (partner→IRAK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of intracellular transport →	+0.068	+0.967	<.001	.001	3	10
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.143	+1.057	<.001	<.001	3	10
OESOPHAGUS	Mitochondrial electron transport, cytochrome c to oxygen →	+0.135	+0.976	<.001	.001	3	9
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.162	+1.061	<.001	<.001	2	10
OESOPHAGUS	Positive regulation of intracellular transport →	+0.076	+0.941	.001	.002	3	9
PANCREAS	Striated muscle contraction →	+0.064	+1.671	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,502 associations by consensus.

Regulation of intracellular transport by IRAK3 expression — OESOPHAGUS

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