IRAK2

Across TCGA patient cohorts, IRAK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,242 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IRAK2-associated proteins across cancer lineages are NADK, CAMP, and ELANE. Each is linked with IRAK2 in more than 6 cancer types. Because this analysis shows association rather than direction, both IRAK2-to-partner and partner-to-IRAK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRAK2 versus NADK in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IRAK2→partner) and Y-score (partner→IRAK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NADK →	+0.431	+0.792	<.001	.001	3	7
UCEC	CAMP →	+1.539	+1.083	<.001	<.001	3	7
UCEC	ELANE →	+0.869	+1.086	<.001	<.001	3	7
GBM	ITGAM →	+0.769	+0.844	<.001	<.001	3	7
UCEC	MMP9 →	+1.192	+1.181	<.001	<.001	3	7
GBM	MPO →	+1.203	+0.730	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,242 associations by consensus.

IRAK2 vs NADK — GBM

Explore this scatter interactively →