IRAK2

Across TCGA cell cohorts, IRAK2 RNA expression is significantly associated with the RNA expression of many other genes, with 10,554 significant associations in total. BONE shows the largest number of these associations.

The most reproducible IRAK2-associated genes across cancer lineages are HRH1, FOSL1, and IL15RA. Each is linked with IRAK2 in more than 12 cancer types. Because this analysis shows association rather than direction, both IRAK2-to-partner and partner-to-IRAK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRAK2 versus HRH1 in BONE, with a Pearson correlation of 0.71.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IRAK2→partner) and Y-score (partner→IRAK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	HRH1 →	+2.953	+1.728	<.001	<.001	3	13
BONE	FOSL1 →	+4.031	+1.320	<.001	<.001	3	12
LUNG_SCLC	IL15RA →	+2.058	+1.271	<.001	.003	2	12
BREAST	SMAD3 →	+1.956	+1.917	<.001	<.001	3	11
KIDNEY	ATG7 →	+1.012	+1.586	.004	<.001	3	11
CNS	SYNJ2 →	+1.803	+1.495	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,554 associations by consensus.

IRAK2 vs HRH1 — BONE

Explore this scatter interactively →