IRAK1BP1

Across TCGA pan-cancer cohorts, IRAK1BP1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated IRAK1BP1 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher IRAK1BP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated IRAK1BP1 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

GBM, UCEC, and HNSC are the cancer types where IRAK1BP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Tertile	All	0.545	0.941	.024	6	view →
UCEC	OS	Median	All	0.414	1.000	.038	4	view →
HNSC	DFS	Tertile	III,IV	0.822	0.273	.038	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

IRAK1BP1–GBM (DFS)

Open the GBM breakdown →