IRAK1BP1

Across TCGA patient cohorts, IRAK1BP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,916 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IRAK1BP1-associated proteins across cancer lineages are PHC1_S664, PLEC_T2735, and PLEC_T2886. Each is linked with IRAK1BP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both IRAK1BP1-to-partner and partner-to-IRAK1BP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRAK1BP1 versus PHC1_S664 in LSCC, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IRAK1BP1→partner) and Y-score (partner→IRAK1BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PHC1_S664 →	+0.903	+0.796	<.001	<.001	3	5
HNSC	PLEC_T2735 →	-0.732	-0.836	<.001	<.001	3	5
HNSC	PLEC_T2886 →	-0.732	-0.836	<.001	<.001	3	5
GBM	PRPF6 →	+0.250	+0.527	<.001	<.001	3	5
GBM	RBM10 →	+0.311	+0.563	<.001	<.001	3	5
OV	CPSF6 →	+0.230	+0.560	.002	.009	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,916 associations by consensus.

IRAK1BP1 vs PHC1_S664 — LSCC

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