IRAK1BP1

Across TCGA patient cohorts, IRAK1BP1 mutation is significantly associated with the RNA expression of many other genes, with 520 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IRAK1BP1-associated genes across cancer lineages are MIR4701, RNU6-1029P, and OR4M2. Each is linked with IRAK1BP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IRAK1BP1-to-partner and partner-to-IRAK1BP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4701 grouped by IRAK1BP1-low versus IRAK1BP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IRAK1BP1→partner) and Y-score (partner→IRAK1BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4701 →	+0.899	+2.708	.001	.003	3	2
SKCM	RNU6-1029P →	+0.220	+3.578	.002	.007	3	2
BRCA	OR4M2 →	+0.034	+8.055	<.001	.007	3	1
UCEC	FADS1 →	+0.791	+3.459	.007	.005	3	1
UCEC	CENPU →	+0.820	+3.212	.005	.009	3	1
UCEC	RAD17 →	+0.578	+3.379	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 520 associations by consensus.

MIR4701 by IRAK1BP1 expression — UCEC

Explore this box plot interactively →