IRAK1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IRAK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,319 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible IRAK1-associated proteins across cancer lineages are HMGB3, CIRBP, and NSDHL. Each is linked with IRAK1 in more than 5 cancer types. Because this analysis shows association rather than direction, both IRAK1-to-partner and partner-to-IRAK1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IRAK1→partner) and Y-score (partner→IRAK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAHMGB3 →+0.784+0.682<.001<.00136
BRCACIRBP →-0.580-0.690<.001.00136
OVNSDHL →+0.517+0.964<.001<.00135
LSCCEIF2AK2 →+0.328+0.555<.001<.00135
OVHPRT1 →+0.523+0.821.005<.00135
UCECPPP1R12C →-0.485-1.004<.001.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,319 associations by consensus.

Exploration