Across TCGA patient cohorts, IRAK1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,489 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible IRAK1-associated genes across cancer lineages are UBL4A, SLC10A3, and SLC6A8. Each is linked with IRAK1 in more than 4 cancer types. Because this analysis shows association rather than direction, both IRAK1-to-partner and partner-to-IRAK1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IRAK1→partner) and Y-score (partner→IRAK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	UBL4A →	+0.554	+0.262	<.001	<.001	3	4
UCEC	SLC10A3 →	+0.647	+0.180	.001	.001	3	4
HNSC	SLC6A8 →	+0.936	+0.361	<.001	<.001	3	4
LUAD	DKC1 →	+0.393	+0.229	.008	.001	3	4
LUAD	CCNQ →	+0.515	+0.278	<.001	<.001	3	4
LUAD	IDS →	+0.561	+0.190	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,489 associations by consensus.

Exploration

IRAK1 survival (RNA) · tumor vs normal (RNA) · all IRAK1 data types