Across TCGA cell cohorts, IRAK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,023 significant associations in total. CNS shows the largest number of these associations.

The most reproducible IRAK1-associated GO terms across cancer lineages are snRNA pseudouridine synthesis, Mitotic spindle elongation, and Peptide antigen transport. Each is linked with IRAK1 in more than 13 cancer types. Because this analysis shows association rather than direction, both IRAK1-to-partner and partner-to-IRAK1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IRAK1→partner) and Y-score (partner→IRAK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	snRNA pseudouridine synthesis →	+0.090	+1.346	<.001	<.001	3	14
SKIN	Mitotic spindle elongation →	+0.221	+1.232	<.001	<.001	3	13
BONE	Peptide antigen transport →	+1.146	+1.700	.001	<.001	3	13
SKIN	Mitotic spindle midzone assembly →	+0.221	+1.232	<.001	<.001	3	13
BLOOD_Lymphoma	Positive regulation of telomerase RNA localization to Cajal body →	+0.096	+1.376	<.001	<.001	2	14
PANCREAS	Positive regulation of DNA-templated DNA replication →	+0.077	+1.022	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,023 associations by consensus.

Exploration

IRAK1 survival (RNA) · tumor vs normal (RNA) · all IRAK1 data types