IRAIN

Across TCGA patient cohorts, IRAIN RNA expression is significantly associated with the protein abundance of many other proteins, with 9,546 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IRAIN-associated proteins across cancer lineages are IGF1R, CBX8, and ACTB. Each is linked with IRAIN in more than 6 cancer types. Because this analysis shows association rather than direction, both IRAIN-to-partner and partner-to-IRAIN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRAIN versus IGF1R in OV, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IRAIN→partner) and Y-score (partner→IRAIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	IGF1R →	+0.691	+0.969	<.001	<.001	3	7
LSCC	CBX8 →	+0.369	+0.837	<.001	<.001	3	4
OV	ACTB →	-0.702	-1.018	.001	<.001	3	4
CCRCC	ARPC3 →	-0.175	-0.793	.009	.001	3	3
CCRCC	RRBP1 →	-0.376	-0.823	.001	.001	3	3
LSCC	SEC24A →	-0.285	-0.701	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,546 associations by consensus.

IRAIN vs IGF1R — OV

Explore this scatter interactively →