IRAG2

Across TCGA patient cohorts, IRAG2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,292 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IRAG2-associated proteins across cancer lineages are DEF6, EVL, and FYB1. Each is linked with IRAG2 in more than 8 cancer types. Because this analysis shows association rather than direction, both IRAG2-to-partner and partner-to-IRAG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IRAG2 versus DEF6 in GBM, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IRAG2→partner) and Y-score (partner→IRAG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DEF6 →	+0.561	+0.640	<.001	<.001	3	9
HNSC	EVL →	+0.696	+0.942	<.001	<.001	3	9
GBM	FYB1 →	+0.772	+0.677	<.001	<.001	3	9
HNSC	PTPN6 →	+0.549	+1.187	<.001	<.001	3	8
UCEC	ARHGAP15 →	+0.712	+0.872	<.001	<.001	3	8
GBM	ARHGAP15_S64 →	+0.785	+0.804	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,292 associations by consensus.

IRAG2 vs DEF6 — GBM

Explore this scatter interactively →