IQUB

Across TCGA patient cohorts, IQUB protein abundance is significantly associated with the RNA expression of many other genes, with 790 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IQUB-associated genes across cancer lineages are XG, RSPH10B2, and WDR86-AS1. Each is linked with IQUB in more than 1 cancer types. Because this analysis shows association rather than direction, both IQUB-to-partner and partner-to-IQUB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IQUB versus XG in UCEC, with a Pearson correlation of 0.92.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IQUB→partner) and Y-score (partner→IQUB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	XG →	+3.975	+1.664	.001	.008	3	2
UCEC	RSPH10B2 →	+2.350	+1.664	.006	.008	3	2
UCEC	WDR86-AS1 →	+4.470	+1.664	.006	.008	3	2
UCEC	ASB2 →	-0.964	-1.664	.004	.008	3	1
UCEC	GIPR →	+2.610	+1.664	.003	.008	3	1
UCEC	TMC5 →	+2.775	+1.664	.007	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 790 associations by consensus.

IQUB vs XG — UCEC

Explore this scatter interactively →