IQUB

Across TCGA cell cohorts, IQUB RNA expression is significantly associated with the go_rna of many other GO terms, with 2,014 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IQUB-associated GO terms across cancer lineages are Process utilizing autophagic mechanism, Autophagy, and Macroautophagy. Each is linked with IQUB in more than 11 cancer types. Because this analysis shows association rather than direction, both IQUB-to-partner and partner-to-IQUB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Process utilizing autophagic mechanism grouped by IQUB-low versus IQUB-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IQUB→partner) and Y-score (partner→IQUB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Process utilizing autophagic mechanism →	+0.056	+0.171	.001	.001	3	12
UPPER_AERODIGESTIVE_TRACT	Autophagy →	+0.056	+0.171	.001	.001	3	12
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.077	+0.214	<.001	.001	3	11
SKIN	Golgi vesicle transport →	+0.045	+0.167	<.001	.005	3	11
LARGE_INTESTINE	Cilium or flagellum-dependent cell motility →	-0.088	-0.123	<.001	.002	3	10
LARGE_INTESTINE	Cilium-dependent cell motility →	-0.088	-0.123	<.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,014 associations by consensus.

Process utilizing autophagic mechanism by IQUB expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →