IQGAP2

Across TCGA patient cohorts, IQGAP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,641 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IQGAP2-associated proteins across cancer lineages are IQGAP2_S1358, IQGAP2_S16, and NOL11. Each is linked with IQGAP2 in more than 8 cancer types. Because this analysis shows association rather than direction, both IQGAP2-to-partner and partner-to-IQGAP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IQGAP2 versus IQGAP2_S1358 in UCEC, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IQGAP2→partner) and Y-score (partner→IQGAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IQGAP2_S1358 →	+0.885	+0.784	<.001	<.001	3	9
LUAD	IQGAP2_S16 →	+0.866	+0.685	<.001	<.001	3	9
LSCC	NOL11 →	-0.335	-0.704	<.001	<.001	3	7
LSCC	UTP15 →	-0.365	-0.715	<.001	<.001	3	7
LSCC	WDR43 →	-0.350	-0.768	<.001	<.001	3	7
LSCC	WDR75 →	-0.362	-0.771	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,641 associations by consensus.

IQGAP2 vs IQGAP2_S1358 — UCEC

Explore this scatter interactively →