IQCG

RNA expression — cross-omics
Cross-omicsRNA → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IQCG RNA expression is significantly associated with the RNA expression of many other genes, with 19,315 significant associations in total. ACC shows the largest number of these associations.

The most reproducible IQCG-associated genes across cancer lineages are NEK11, WDR19, and LMLN. Each is linked with IQCG in more than 31 cancer types. Because this analysis shows association rather than direction, both IQCG-to-partner and partner-to-IQCG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IQCG versus NEK11 in KIRP, with a Pearson correlation of 0.84.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCG→partner) and Y-score (partner→IQCG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIRPNEK11 →+1.160+0.927<.001<.001332
UVMWDR19 →+1.052+0.709<.001<.001332
KIRPLMLN →+0.991+0.902<.001<.001332
UCECOSCP1 →+1.142+1.185<.001<.001331
KIRPCCDC191 →+1.232+0.863<.001<.001331
UVMMFN1 →+1.642+0.797<.001<.001331
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,315 associations by consensus.

IQCG vs NEK11 — KIRP

Per-sample scatter of IQCG vs NEK11 in KIRP (Pearson r = 0.84).

Explore this scatter interactively →

Exploration