IQCG

Across TCGA patient cohorts, IQCG RNA expression is significantly associated with the protein abundance of many other proteins, with 9,590 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible IQCG-associated proteins across cancer lineages are UBXN7, RUVBL2, and MLF1_S34. Each is linked with IQCG in more than 5 cancer types. Because this analysis shows association rather than direction, both IQCG-to-partner and partner-to-IQCG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IQCG versus UBXN7 in HNSC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCG→partner) and Y-score (partner→IQCG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	UBXN7 →	+0.491	+0.764	<.001	<.001	3	6
UCEC	RUVBL2 →	+0.298	+0.896	<.001	<.001	3	6
LSCC	MLF1_S34 →	+0.742	+0.595	<.001	<.001	3	5
GBM	LZTFL1 →	+0.417	+0.637	<.001	<.001	3	5
GBM	C7orf57_S209 →	+1.463	+0.602	<.001	<.001	3	4
OV	DLG1 →	+0.363	+0.610	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,590 associations by consensus.

IQCG vs UBXN7 — HNSC

Explore this scatter interactively →