Across TCGA pan-cancer cohorts, IQCF5 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated IQCF5 data layer.
The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher IQCF5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated IQCF5 expression acts as an unfavorable survival marker, although some lineages such as TGCT show a favorable association.
BLCA, ACC, and CESC are the cancer types where IQCF5 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.