IQCF4P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, IQCF4P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of IQCF4P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where IQCF4P RNA is repressed in tumor relative to normal tissue. In most cancer types IQCF4P is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, UCEC, and KIRP are the cancer types where IQCF4P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IQCF4P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCMaleAll−0.020<.0015view →
UCECAllAll+0.066.0114view →
KIRPMaleAll−0.022.0491view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration