IQCF3

Across TCGA patient cohorts, IQCF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,759 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IQCF3-associated GO terms across cancer lineages are Positive regulation of DNA repair, tRNA metabolic process, and Methylation. Each is linked with IQCF3 in more than 12 cancer types. Because this analysis shows association rather than direction, both IQCF3-to-partner and partner-to-IQCF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by IQCF3-low versus IQCF3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCF3→partner) and Y-score (partner→IQCF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA repair →	+0.065	+0.045	<.001	<.001	3	13
STAD	tRNA metabolic process →	+0.074	+0.044	<.001	<.001	3	13
STAD	Methylation →	+0.064	+0.047	<.001	<.001	3	13
STAD	Oxidative phosphorylation →	+0.083	+0.040	<.001	<.001	3	12
STAD	Nucleotide-excision repair →	+0.059	+0.039	<.001	<.001	3	12
STAD	Aerobic respiration →	+0.084	+0.041	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,759 associations by consensus.

Positive regulation of DNA repair by IQCF3 expression — STAD

Explore this box plot interactively →