IQCF3

Across TCGA cell cohorts, IQCF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 206 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IQCF3-associated GO terms across cancer lineages are Positive regulation of cold-induced thermogenesis, Microtubule bundle formation, and Regulation of complement-dependent cytotoxicity. Each is linked with IQCF3 in more than 2 cancer types. Because this analysis shows association rather than direction, both IQCF3-to-partner and partner-to-IQCF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cold-induced thermogenesis grouped by IQCF3-low versus IQCF3-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCF3→partner) and Y-score (partner→IQCF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Positive regulation of cold-induced thermogenesis →	+0.033	+0.075	.001	.003	3	3
BLOOD_Leukemia	Microtubule bundle formation →	-0.019	-0.092	.005	.005	3	3
BLOOD_Leukemia	Regulation of complement-dependent cytotoxicity →	+0.192	+0.085	.004	.006	3	3
BLOOD_Leukemia	Sulfur compound biosynthetic process →	+0.042	+0.092	<.001	.004	3	3
BLOOD_Leukemia	Nuclear receptor-mediated signaling pathway →	+0.033	+0.092	<.001	.004	3	2
BLOOD_Leukemia	Negative regulation of response to endoplasmic reticulum stress →	+0.081	+0.137	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 206 associations by consensus.

Positive regulation of cold-induced thermogenesis by IQCF3 expression — BLOOD_Leukemia

Explore this box plot interactively →