Across TCGA patient cohorts, IQCF2 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IQCF2-associated genes across cancer lineages are TRAJ34, LMX1A-AS2, and MIR3713. Each is linked with IQCF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IQCF2-to-partner and partner-to-IQCF2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCF2→partner) and Y-score (partner→IQCF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRAJ34 →	+0.614	+2.475	.006	.009	3	2
LUAD	LMX1A-AS2 →	+0.422	+5.217	<.001	.007	3	2
UCEC	MIR3713 →	+0.361	+4.049	<.001	.008	3	1
SKCM	MIR3134 →	+0.492	+4.215	.005	.009	3	1
UCEC	LINC00544 →	+0.135	+2.633	<.001	.008	3	1
SKCM	RN7SL831P →	+0.151	+6.219	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

IQCF2 survival (RNA) · tumor vs normal (RNA) · all IQCF2 data types