Across TCGA patient cohorts, IQCF2 mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IQCF2-associated genes across cancer lineages are aDC, Adipocytes, and Erythrocytes. Each is linked with IQCF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IQCF2-to-partner and partner-to-IQCF2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCF2→partner) and Y-score (partner→IQCF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	aDC →	+0.126	+3.008	.001	.019	3	1
UCEC	Adipocytes →	+0.036	+3.729	<.001	.002	3	1
UCEC	Erythrocytes →	+0.034	+2.879	.011	.033	3	1
UCEC	Hepatocytes →	+0.014	+2.899	.016	.040	3	1
UCEC	Skeletal muscle →	+0.059	+3.180	.014	.010	3	1
UCEC	Neurons →	+0.030	+3.191	.004	.010	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

IQCF2 survival (RNA) · tumor vs normal (RNA) · all IQCF2 data types