IQCF1

Across TCGA cell cohorts, IQCF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 785 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IQCF1-associated GO terms across cancer lineages are Myeloid cell apoptotic process, rRNA metabolic process, and Mitochondrial mRNA catabolic process. Each is linked with IQCF1 in more than 4 cancer types. Because this analysis shows association rather than direction, both IQCF1-to-partner and partner-to-IQCF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myeloid cell apoptotic process grouped by IQCF1-low versus IQCF1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCF1→partner) and Y-score (partner→IQCF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Myeloid cell apoptotic process →	+0.143	+0.081	<.001	.001	3	5
LUNG_NSCLC_LUAD	rRNA metabolic process →	+0.037	+0.059	.004	.006	2	5
LUNG_NSCLC_LUAD	Mitochondrial mRNA catabolic process →	+0.069	+0.081	.002	.005	3	4
BLOOD_Lymphoma	Negative regulation of intrinsic apoptotic signaling pathway →	+0.065	+0.089	<.001	.002	3	4
BLOOD_Lymphoma	Negative regulation of protein catabolic process →	+0.036	+0.082	.004	.006	3	4
BLOOD_Lymphoma	Protein folding →	+0.038	+0.079	.003	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 785 associations by consensus.

Myeloid cell apoptotic process by IQCF1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →