IQCE

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IQCE RNA expression is significantly associated with the protein abundance of many other proteins, with 11,312 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IQCE-associated proteins across cancer lineages are COG3, COG4, and DAP_S51. Each is linked with IQCE in more than 4 cancer types. Because this analysis shows association rather than direction, both IQCE-to-partner and partner-to-IQCE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IQCE versus COG3 in UCEC, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCE→partner) and Y-score (partner→IQCE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCOG3 →+0.252+0.601<.001<.00134
UCECCOG4 →+0.197+0.501.001.00134
PDACDAP_S51 →+0.722+0.346.001.00134
UCECDECR2 →+0.517+0.717<.001<.00134
GBMGTF2I →+0.408+0.694<.001<.00134
GBMMICALL1 →-0.409-0.565<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,312 associations by consensus.

IQCE vs COG3 — UCEC

Per-sample scatter of IQCE vs COG3 in UCEC (Pearson r = 0.31).

Explore this scatter interactively →

Exploration