IQCE

Across TCGA cell cohorts, IQCE RNA expression is significantly associated with the go_rna of many other GO terms, with 4,660 significant associations in total. CNS shows the largest number of these associations.

The most reproducible IQCE-associated GO terms across cancer lineages are Cilium-dependent cell motility, Cilium movement involved in cell motility, and Cilium or flagellum-dependent cell motility. Each is linked with IQCE in more than 14 cancer types. Because this analysis shows association rather than direction, both IQCE-to-partner and partner-to-IQCE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium-dependent cell motility grouped by IQCE-low versus IQCE-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCE→partner) and Y-score (partner→IQCE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.100	-0.873	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.104	-0.873	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.100	-0.873	<.001	<.001	3	15
LUNG_NSCLC_LUAD	Negative regulation of autophagy →	+0.059	+0.698	<.001	.001	3	14
BONE	Pre-mRNA catabolic process →	+0.220	+0.891	<.001	.005	3	14
LUNG_SCLC	Sperm motility →	-0.108	-0.845	.002	.006	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,660 associations by consensus.

Cilium-dependent cell motility by IQCE expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →