IQCA1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IQCA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,351 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IQCA1-associated proteins across cancer lineages are DPYSL3, PXDN, and OLFML3. Each is linked with IQCA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both IQCA1-to-partner and partner-to-IQCA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IQCA1 versus DPYSL3 in COAD, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCA1→partner) and Y-score (partner→IQCA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADDPYSL3 →+0.605+0.249<.001<.00136
BRCAPXDN →+0.514+0.801.001<.00135
BRCAOLFML3 →+0.974+1.085<.001<.00135
BRCAPHLDB1 →+0.411+1.020<.001<.00135
BRCAAEBP1 →+0.917+1.200<.001<.00135
COADCOL1A1 →+0.760+0.278<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,351 associations by consensus.

IQCA1 vs DPYSL3 — COAD

Per-sample scatter of IQCA1 vs DPYSL3 in COAD (Pearson r = 0.41).

Explore this scatter interactively →

Exploration