IQCA1

Across TCGA patient cohorts, IQCA1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,677 significant associations in total. OV shows the largest number of these associations.

The most reproducible IQCA1-associated genes across cancer lineages are CD276, VWF, and CHPF. Each is linked with IQCA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IQCA1-to-partner and partner-to-IQCA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IQCA1 versus CD276 in GBM, with a Pearson correlation of 0.93.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCA1→partner) and Y-score (partner→IQCA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CD276 →	+0.951	+1.013	<.001	<.001	3	1
GBM	VWF →	+0.753	+1.013	.009	<.001	3	1
GBM	CHPF →	+0.906	+1.013	.003	<.001	3	1
GBM	H1-1 →	-2.160	-1.126	.006	.001	3	1
GBM	CA6 →	-0.180	-1.259	.001	<.001	3	1
GBM	AHI1 →	-0.970	-1.146	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,677 associations by consensus.

IQCA1 vs CD276 — GBM

Explore this scatter interactively →