IQCA1

Across TCGA cell cohorts, IQCA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,527 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible IQCA1-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Nuclear export, and Indole-containing compound biosynthetic process. Each is linked with IQCA1 in more than 7 cancer types. Because this analysis shows association rather than direction, both IQCA1-to-partner and partner-to-IQCA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by IQCA1-low versus IQCA1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCA1→partner) and Y-score (partner→IQCA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of myoblast fusion →	+0.092	+1.317	<.001	<.001	3	8
OESOPHAGUS	Nuclear export →	+0.075	+0.835	.001	.008	3	7
LUNG_SCLC	Indole-containing compound biosynthetic process →	-1.106	-1.073	.006	.004	3	7
OESOPHAGUS	Ribonucleotide biosynthetic process →	+0.119	+1.697	<.001	<.001	3	7
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.099	+1.868	<.001	<.001	3	7
OVARY	Negative regulation of RNA splicing →	+0.052	+1.001	.001	.006	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,527 associations by consensus.

Negative regulation of myoblast fusion by IQCA1 expression — OVARY

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