Across TCGA patient cohorts, IQANK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,445 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IQANK1-associated proteins across cancer lineages are SCRIB, FAM83H, and PYCR3. Each is linked with IQANK1 in more than 7 cancer types. Because this analysis shows association rather than direction, both IQANK1-to-partner and partner-to-IQANK1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IQANK1→partner) and Y-score (partner→IQANK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SCRIB →	+0.368	+0.790	<.001	<.001	3	8
LSCC	FAM83H →	+0.577	+1.104	<.001	<.001	3	8
COAD	PYCR3 →	+0.373	+0.918	<.001	<.001	3	7
COAD	NUDCD1 →	+0.444	+0.904	<.001	<.001	3	6
OV	AGO2 →	+0.367	+1.236	<.001	<.001	3	6
UCEC	ESRP1 →	+0.756	+1.132	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,445 associations by consensus.

Exploration

IQANK1 survival (RNA) · tumor vs normal (RNA) · all IQANK1 data types