IPPK

Across TCGA patient cohorts, IPPK protein abundance is significantly associated with the RNA expression of many other genes, with 10,320 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IPPK-associated genes across cancer lineages are OLR1, RNU6-53P, and LINC01210. Each is linked with IPPK in more than 1 cancer types. Because this analysis shows association rather than direction, both IPPK-to-partner and partner-to-IPPK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IPPK versus OLR1 in UCEC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IPPK→partner) and Y-score (partner→IPPK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OLR1 →	+1.248	+1.177	.009	.002	3	2
UCEC	RNU6-53P →	+1.553	+1.496	<.001	.004	3	2
HNSC	LINC01210 →	-0.858	-0.553	.007	<.001	3	2
LSCC	YPEL1 →	-0.668	-0.540	<.001	<.001	3	2
HNSC	RHOXF1 →	-0.533	-0.600	<.001	<.001	3	2
HNSC	IQCE →	-0.713	-0.621	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,320 associations by consensus.

IPPK vs OLR1 — UCEC

Explore this scatter interactively →