IPPK

Across TCGA cell cohorts, IPPK RNA expression is significantly associated with the go_rna of many other GO terms, with 3,487 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IPPK-associated GO terms across cancer lineages are Positive regulation of mRNA 3'-end processing, Regulatory ncRNA-mediated gene silencing, and RNA export from nucleus. Each is linked with IPPK in more than 14 cancer types. Because this analysis shows association rather than direction, both IPPK-to-partner and partner-to-IPPK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mRNA 3'-end processing grouped by IPPK-low versus IPPK-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IPPK→partner) and Y-score (partner→IPPK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of mRNA 3'-end processing →	+0.178	+0.963	.001	.001	3	15
STOMACH	Regulatory ncRNA-mediated gene silencing →	+0.110	+0.987	<.001	<.001	3	14
BONE	RNA export from nucleus →	+0.106	+0.637	.009	.001	3	14
BONE	Nucleic acid transport →	+0.110	+0.481	.002	.008	3	13
BONE	RNA transport →	+0.110	+0.481	.002	.008	3	13
BONE	mRNA transport →	+0.117	+0.620	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,487 associations by consensus.

Positive regulation of mRNA 3'-end processing by IPPK expression — OESOPHAGUS

Explore this box plot interactively →