Across TCGA patient cohorts, IPP RNA expression is significantly associated with the protein abundance of many other proteins, with 12,208 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IPP-associated proteins across cancer lineages are EVI2B, UBE2J1, and CTSS. Each is linked with IPP in more than 5 cancer types. Because this analysis shows association rather than direction, both IPP-to-partner and partner-to-IPP results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IPP→partner) and Y-score (partner→IPP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	EVI2B →	-0.651	-0.540	<.001	<.001	3	6
LSCC	UBE2J1 →	-0.466	-0.350	<.001	<.001	3	5
GBM	CTSS →	-0.525	-0.315	<.001	.003	3	5
GBM	PTPRC →	-0.728	-0.489	<.001	<.001	3	5
GBM	RPS8_S160 →	-0.745	-0.510	.001	.002	3	5
GBM	VAV1 →	-0.621	-0.419	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,208 associations by consensus.

Exploration

IPP survival (RNA) · tumor vs normal (RNA) · all IPP data types