Across TCGA patient cohorts, IPP mutation is significantly associated with the RNA expression of many other genes, with 1,957 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IPP-associated genes across cancer lineages are FAM47DP, RN7SL22P, and NAMPTP2. Each is linked with IPP in more than 2 cancer types. Because this analysis shows association rather than direction, both IPP-to-partner and partner-to-IPP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IPP→partner) and Y-score (partner→IPP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	FAM47DP →	+0.016	+4.544	<.001	.009	3	3
LIHC	RN7SL22P →	+0.220	+4.647	<.001	.007	3	3
LUSC	NAMPTP2 →	+0.257	+4.724	<.001	.005	3	3
SKCM	NIPA2P2 →	+0.027	+4.147	<.001	.008	3	3
LIHC	SGO1P1 →	+0.034	+5.902	<.001	.001	3	2
LIHC	RNU6-1107P →	+0.357	+6.169	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,957 associations by consensus.

Exploration

IPP survival (RNA) · tumor vs normal (RNA) · all IPP data types