Across TCGA patient cohorts, IPO9 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,333 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IPO9-associated proteins across cancer lineages are C1orf35, ADAR, and GATAD2B. Each is linked with IPO9 in more than 8 cancer types. Because this analysis shows association rather than direction, both IPO9-to-partner and partner-to-IPO9 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IPO9→partner) and Y-score (partner→IPO9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	C1orf35 →	+0.489	+0.622	<.001	<.001	3	9
LSCC	ADAR →	+0.270	+0.563	<.001	<.001	3	8
HNSC	GATAD2B →	+0.323	+0.530	<.001	<.001	3	8
LSCC	NXF1 →	+0.228	+0.520	<.001	<.001	3	8
GBM	CDC73 →	+0.311	+0.576	<.001	<.001	3	8
BRCA	YTHDC1 →	+0.282	+0.433	.003	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,333 associations by consensus.

Exploration

IPO9 survival (RNA) · tumor vs normal (RNA) · all IPO9 data types